Does Semaglutide Cause Hair Loss Problems in Men?

Does Semaglutide Cause Hair Loss Problems

Maria Harutyunyan Jul 21, 2025

As Wegovy (Semaglutide) becomes popular for weight loss and type 2 diabetes management, a growing number of people are asking a pressing question: Does semaglutide cause hair loss problems? 

Many individuals have noticed increased hair shedding after starting Semaglutide, sparking ongoing conversations among both patients and healthcare providers. While not everyone experiences this, the pattern is becoming harder to dismiss. The underlying causes remain unclear; it could be a direct result of the drug, a side effect of rapid weight loss, or tied to other changes happening within the body.

In this blog, we'll take a closer look at what the latest research and medical insights reveal. We'll examine whether the hair loss is caused directly by Semaglutide or indirectly through its effects, explore common risk factors, share practical prevention tips, and explain how Spartan can support your overall health while helping you maintain your hair.

What Is Semaglutide and How It Works

Semaglutide is a medication used to treat type 2 diabetes and support weight loss. It is marketed under brand names such as Ozempic and Wegovy. This drug works by acting like a natural hormone in the body called GLP-1. The hormone regulates blood sugar levels, suppresses appetite, and slows down digestion.

One of the primary ways semaglutide helps in weight loss is by increasing feelings of fullness. As a result, you eat less without feeling like you are starving. It also slows how quickly food leaves your stomach. This prevents blood sugar from rising too quickly after meals. These changes support steady weight loss and improved glucose control over time.

Although the medication does not directly target hair or hormones associated with hair growth, it can still have indirect effects. Fast weight loss can place stress on the body. The body may then focus on more vital functions and reduce support for things like hair growth. 

Changes in eating habits, calorie intake, and nutrient absorption may also affect hair health. This does not happen to everyone, but it explains why some people may notice more hair shedding while using semaglutide.

Hair Loss: Direct Drug Effect vs. Telogen Effluvium

Semaglutide does not damage hair follicles. That means the medication itself is unlikely to harm your hair through a direct reaction. However, some people still notice more hair falling out after starting semaglutide, especially during the first few months.

The most common reason for this type of hair loss is called telogen effluvium. This condition happens when the body pushes more hair follicles into a resting phase. Those hairs then fall out a few weeks later. A major change in the body, such as rapid weight loss, often triggers this process. Since semaglutide can lead to rapid weight loss, this is likely the link between the drug and hair shedding.

Other factors may also be involved. Some people eat less or change their diets during treatment, which can lead to lower intake of key nutrients. When the body does not get enough protein, iron, or certain vitamins, hair growth may slow down. Additionally, hormonal shifts and physical stress also add to this effect. Together, these changes can cause temporary hair loss while the body adjusts.

What the Evidence Says

Research on semaglutide and hair loss is still in development, but recent data provide a clearer picture of what users may experience. A recent study compared hair loss rates in people using different weight loss medications. The study compared users of semaglutide (Ozempic and Wegovy) with those taking bupropion and naltrexone (sold together as Contrave). The findings showed that users of semaglutide were more than twice as likely to be diagnosed with hair loss.

To be more specific, the study reported approximately 26.5 hair loss diagnoses per 1,000 person-years among users of semaglutide. In contrast, Contrave users experienced only 11.8 cases per 1,000. Women seemed to be more affected. The risk for women taking semaglutide was roughly double compared to women on Contrave. Although this does not prove that semaglutide causes hair loss directly, it raises concern about its possible connection, especially in female users.

Data from clinical trials of Wegovy (a high-dose form of semaglutide used for weight loss) also reflect this trend. In these trials, about 3% of users reported hair loss. Among those taking a placebo, only around 1% experienced the same. Although these numbers appear low, they still show a noticeable difference between those on the drug and those who were not. The manufacturer does not state hair loss as a common side effect, since it falls below the 5% threshold used in labeling. Still, it has been acknowledged by the Food and Drug Administration in review documents and official product information.

Putting all this together, the overall risk of hair loss from semaglutide appears relatively low but not negligible. It appears to be more common in individuals who lose weight rapidly, particularly women. The combination of rapid body changes, hormonal shifts, and nutritional factors may make some individuals more prone to hair shedding during treatment. These findings do not apply to everyone, but they suggest that hair changes are a real possibility for certain users.

Who's at Risk?

Hair loss with semaglutide does not affect everyone; however, some individuals are more likely to experience it than others. But certain patterns can help explain who may be at higher risk.

Rapid weight loss is a major factor. When someone loses more than 10 to 20% of their body weight in just a few months, the body may respond by slowing or stopping hair growth. This is a natural response to sudden physical changes. When you lose weight quickly, your body sees it as a type of stress. As a result, it may slow down non-essential functions, such as hair growth.

Women appear to be more affected than men. Research shows that women taking semaglutide are at about twice the risk of hair loss compared to those on other medications. Hormonal differences and faster body changes may contribute to this.

Poor nutrition can also increase risk. Eating less may lead to low levels of protein, iron, zinc, or biotin. These nutrients are important for hair health. Inconsistent eating patterns or high stress levels during treatment can increase the likelihood of shedding. 

Typical Timeline and Duration

Hair loss from semaglutide usually begins two to four months after weight loss starts. This delay happens because hair does not fall out immediately. When the body changes, such as rapid weight loss, hair follicles can shift into a resting phase. A few months later, the hair sheds as part of that natural cycle. That is why people may not notice hair loss until well after they have begun losing weight.

This type of hair loss is usually temporary. It typically resolves once the body has adjusted. In most cases, hair starts growing back within six to nine months. The process may feel slow, but steady regrowth is a common occurrence. The body just needs time to find a new balance.

Permanent hair loss is rare during the use of semaglutide. It is more likely in cases where the body is under extreme stress or has inadequate nutrition. Losing too much weight too quickly or missing key nutrients, such as protein, can exacerbate the situation. 

Prevention and Management Strategies

Hair loss during semaglutide treatment can be frustrating, but it is often manageable. Most of the time, it occurs due to changes in the body, rather than direct damage to the hair. Here's how you can reduce shedding and support regrowth:

  1. Nutrition and Supplements

What you eat plays a big role in how your hair grows. Hair needs protein to grow well. When your diet lacks enough protein, the body focuses on more important functions and slows hair growth. This is common when eating less during weight loss.

Nutrients like iron, zinc, biotin, vitamin D, and B vitamins support healthy hair. Low iron levels, even without anemia, can lead to increased shedding. Zinc supports hair tissue repair, while biotin and B vitamins help with follicle function and overall strength. Vitamin D impacts the hair cycle and is often deficient in individuals who experience rapid weight loss.

If your regular meals do not consistently provide these nutrients, a gentle multivitamin can help fill the gaps. For people taking GLP-1 medications, this is a simple way to give your body the support it needs without increasing appetite or calorie intake.

  1. Stress Management

Stress is another common contributor to hair loss. Physical stress from weight loss and emotional stress from adjusting to a new routine can both affect the body. These changes may lead to temporary shedding, often months after the stress begins.

Mindfulness exercises, such as breathing or meditation, can help calm the nervous system. Gentle yoga is another way to lower tension while staying active. Scalp massage may improve circulation and reduce tension. Lowering stress may not completely stop hair loss, but it can help reduce its intensity and support recovery.

  1. Hair-Friendly Habits

How you care for your hair makes a difference, especially when it is already shedding. Use mild shampoos without harsh ingredients. Avoid washing with hot water and let your hair air-dry or use the lowest heat setting when necessary.

Be gentle when brushing or styling. A wide-tooth comb is easier on hair than a fine brush, and it's best to avoid tight hairstyles that pull at the roots.

  1. Medical Treatments

Some people may benefit from treatments that support regrowth. One option is minoxidil, which increases blood flow to the scalp. It is available as a topical foam or liquid, and in some cases, as a low-dose pill.

Another treatment option is platelet-rich plasma (PRP) therapy. In this treatment, growth factors are injected from your own blood into your scalp. Another option is low-level laser therapy, which uses light to support hair follicle activity. These treatments are generally safe but should be discussed with a doctor to see if they are right for your situation.

  1. Adjusting the Weight Loss Rate

One of the most effective ways to protect your hair is to slow down the rate of weight loss. Rapid weight changes often trigger shedding. Slower, steady weight loss gives the body time to adjust and reduces stress on the system.

Discuss with your provider the possibility of adjusting your pace. This involves adjustments to dose, diet, or activity. A moderate approach is easier to manage and may help your body keep more of its hair during treatment.

Spartan's Role and Product Integration

Changes in hair texture during semaglutide use can be frustrating, especially when weight loss affects your dietary intake. Spartan offers products that support hair and scalp health during this time. Their formulas are made to help restore nutrients, strengthen hair, and improve scalp condition. These products can be added to your routine without making major changes.

  • The Root Activator Shampoo protects the scalp and supports hair follicles. It includes ingredients such as biotin and collagen, which help improve hair strength and texture.
  • The Root Activator Conditioner adds moisture and reduces breakage, making hair easier to manage and style.
  • For targeted use, the Root Activator Spray for Men is applied to the scalp to support growth where thinning is more noticeable.

These products do not replace medical care, but they can work well with semaglutide. When used regularly, and along with a balanced diet and slow weight loss, they may help reduce shedding and support healthier hair.

Real-Life Examples and Testimonials

Many people who use semaglutide have reported similar experiences with hair loss. 

One user, Sarah M., shared her experience: "I lost over 20 pounds in three months, and by month four, my hair started thinning. My doctor said it was likely due to the rapid weight loss. I started using the Spartan Root Activator Shampoo and Conditioner along with their scalp spray. After six weeks, I noticed less hair in the shower and my scalp felt healthier. By month seven, my hair looked fuller again."

Others have shared similar outcomes. A user said on a Reddit hair loss sub, "The Root Spray helped my hair feel stronger. I also added more protein to my diet and used a multivitamin. That combination made a big difference."

FAQs

Will I go bald if I take semaglutide?

No. Most hair loss from semaglutide is temporary. It usually happens because of fast weight loss, not the medicine itself. Hair grows back once your body adjusts.

How long until the shedding stops?

Hair shedding often slows down within two to four months after your weight becomes steady. Regrowth usually starts a few months later.

Should I stop GLP-1 drugs if I lose hair?

Do not stop taking the medicine without consulting your doctor. Instead, focus on eating well, managing stress, and caring for your hair properly.

Is hair loss different between Ozempic, Wegovy, and Mounjaro?

No. These medicines work similarly. Hair loss depends more on how fast you lose weight than on which brand you take.

Conclusion

Semaglutide does not directly cause hair loss, but it may lead to shedding for some people during fast weight loss. This usually happens because the body goes through changes like lower calorie intake, nutrient gaps, or stress. These factors can trigger a temporary hair shedding condition called telogen effluvium.

Hair often begins to grow back within a few months once the body has stabilized and adjusted. While the loss can feel distressing, it is rarely permanent. Most people see improvement with consistent care and attention to their health.

To support your hair during this time, maintain a balanced diet, manage stress effectively, and be gentle with your hair. Simple changes can help protect your hair's health. Spartan products can also support your scalp and hair through nutrient-based formulas that work in conjunction with your weight loss routine. With early care and consistent habits, most people recover well and regain full hair growth over time.